ceesdekker.net for Dummies

ceesdekker.net for Dummies

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2009, discovery of a new phenotype for microbes in narrow nanofluidic slits; and first detection of nearby protein structures alongside DNA employing reliable-condition nanopores

You regularly become involved in discussions about science and religion. You've got also written various publications on the topic. Don’t you feel that in some unspecified time in the future We are going to know every thing Which God’s role might be more than?

[Laughs] ‘It absolutely was unquestionably an awesome hazard! At enough time, I had been very well informed that it could go Mistaken and that I could turn out to be much less successful, but I just disregarded that. Curiosity has generally been my strongest driving pressure. And fortuitously it all labored out.’

Since 2000, Dekker has shifted the key concentration of his work in direction of biophysics where by he research the Homes of one biomolecules and cells utilizing the tools of nanotechnology. This variation of subject was pushed by his fascination for the outstanding working of Organic molecular buildings, along with from the extended-expression point of view that lots of exciting discoveries might be envisioned in this area.[5] Latest lines of exploration in his biophysics team are in the areas of:[6]

This yielded a breakthrough. Inside only some months, we had been able to measure transportation by means of somebody solitary-walled carbon nanotube. Based on very low-temperature experiments by a brilliant PhD scholar in my group, Sander Tans (now a valued colleague and professor at Delft University of Technology using an Lively investigation lab at AMOLF in Amsterdam), we showed that carbon nanotubes ended up genuine quantum wires with quite long (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic conduct.

Microbiology has only been around for the century, due to the fact we began to analyze micro-organisms more seriously. I thought nanobiology was an proper phrase, due to the fact all molecular Organic suitable interactions happen for the nanoscale: a protein is some nanometres in sizing, DNA is two nm thick.’

We use nanofabricated microfluidic structures to pattern spatial boundaries for microbes and biomimetic vesicles with reconstituted protein networks which evaluate the basic position of spatial confinement for the molecular and mobile degree. Our tasks contain the following:

Dynamic ParB–DNA interactions initiate and maintain a partition condensate for bacterial chromosome segregation

‘Of course, I comprehend persons had been amazed at the time. At the end of the nineties, After i was in my forties, I was Professor of Molecular Electronics and I have to confess that it experienced become a bit bored, I didn’t master A lot anymore. The sphere went much more into the appliance facet, how you can integrate nanotubes into Digital circuits.

Resolving the action dimensions in condensin-pushed DNA loop extrusion identifies ATP binding as being the action-creating approach

Due to the fact 2000 he moved to solitary-molecule biophysics and nanobiology, with study from experiments of DNA loop extrusion and supercoiling to DNA translocation through nanopores. Far more not too long ago his investigate has focused on studying chromatin framework and cell division with microbes on chip, although he is also aiming to ultimately Create synthetic cells from the bottom up.

Nanoscientist Cees Dekker is definitely an amiable and flamboyant guy who seems Substantially youthful as opposed to 62 a long time he really is – fashionable Eyeglasses, psychedelic shirt, participating smile – but not a person to squander time. He will take his time, but no more than vital.

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It was an extremely attention-grabbing time, throughout which I acquired loads of help from cees dekker Delft College of Technology, in which I used to be a professor at some time, and I began many collaborations with molecular biologists. That served me learn a great deal.’